Cart
sales@molnova.com
Closantel sodium
CAS No. 61438-64-0
Closantel sodium( —— )
Catalog No. M15316 CAS No. 61438-64-0
A veterinary anthelmintic with known proton ionophore activities; is identified as a potent and specific inhibitor of filarial chitinases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 31 | In Stock |
|
| 100MG | 45 | In Stock |
|
| 200MG | 71 | In Stock |
|
| 500MG | 133 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameClosantel sodium
-
NoteResearch use only, not for human use.
-
Brief DescriptionA veterinary anthelmintic with known proton ionophore activities; is identified as a potent and specific inhibitor of filarial chitinases.
-
DescriptionA veterinary anthelmintic with known proton ionophore activities; is identified as a potent and specific inhibitor of filarial chitinases; also shows to be an allosteric inhibitor of SPAK and OSR1.Parasite Infection Approved(In Vitro):Closantel sodium, a known anthelmintic drug, is highly specific forfilarial family chitinases compared to those fromprotozoans and the human chitinase, human chitotriosidase.
-
In VitroClosantel sodium, a known anthelmintic drug, is highly specific forfilarial family chitinases compared to those fromprotozoans and the human chitinase, human chitotriosidase.
-
In Vivo——
-
Synonyms——
-
PathwayMicrobiology/Virology
-
TargetParasite
-
RecptorOthers
-
Research AreaInfection
-
IndicationParasite Infection
Chemical Information
-
CAS Number61438-64-0
-
Formula Weight685.0555
-
Molecular FormulaC22H13Cl2I2N2NaO2
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESCC1=CC(=C(C=C1NC(=O)C2=C(C(=CC(=C2)I)I)O)Cl)C(C#N)C3=CC=C(C=C3)Cl.[Na]
-
Chemical NameBenzamide, N-[5-chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodo-, sodium salt (1:1)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. AlAmri MA, et al. ChemMedChem. 2017 May 9;12(9):639-645.
2. Gloeckner C, et al. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3424-9.
molnova catalog
related products
-
Antitrypanosomal age...
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM).
-
AQ-13 dihydrochlorid...
AQ-13 dihydrochloride is an antimalarial drug. It is effective against drug-resistant strains of Plasmodium falciparum.
-
Spirodiclofen
Spirodiclofen is a selective, non-systemic acaricide from the new chemical class of tetronic acid derivatives,with no cross resistance to currently available acaricides and with additional insecticidal properties.
